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Lorazepam: No dose adjustment is necessary for gentle-to-reasonable renal impairment; not recommended for sufferers with renal failureAvailable facts from released observational scientific studies of pregnant Gals exposed to benzodiazepines don't report a clear association with benzodiazepines and significant beginning defects (see Facts).When benz

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In patients by now getting an opioid analgesic, prescribe a reduce Preliminary dose of diazepam tablets than indicated in the absence of the opioid and titrate determined by clinical reaction. If an opioid is initiated in the patient already having diazepam tablets, prescribe a reduced First dose from the opioid and titrate based mostly upon clinic

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